Fixing the Flaws in AlphaFold’s Interface Scoring: Meet Dunbrack’s ipSAE
Predicting protein-protein interactions Since AlphaFold2 was published, one of the major applications of the model was accurately predicting the structure of...
Blog
Thoughts and perspectives from the Levitate Team
2025
Design de novo antibody-antigen interactions with RFantibody
Designing an antibody from scratch to bind a specific site on a target protein has traditionally required immunization or large-scale library screening. But ...
Improving Binder Success Rates with BindCraft
We’re excited to announce that BindCraft1 has been added to our toolset at Levitate Bio! This protocol has huge potential for improving de novo binder design...
2024
Alphafold Initial Guess
Enhancing De Novo Binder Design with Initial Guess
Mitigating Manufacturing Liabilities with Post-Translational Modification Prediction
Maintaining therapeutic stability and potency during manufacturing and storage continues to be a costly and significant challenge in development. Protein the...
RosettaCon: A Glimpse into the Future
Observations and thoughts from Summer RosettaCon 2024.